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'''Pipramadol''' is an ] with potent ] properties.<ref>{{cite journal |last1=Huegi |first1=Bruno S. |last2=Ebnoether |first2=Anton M. |last3=Rissi |first3=Erwin |last4=Gadient |first4=Fulvio |last5=Hauser |first5=Daniel |last6=Roemer |first6=Dietmar |last7=Buescher |first7=Heinz H. |last8=Petcher |first8=Trevor J. |title=Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties |journal=Journal of Medicinal Chemistry |date=January 1983 |volume=26 |issue=1 |pages=42–50 |doi=10.1021/jm00355a010}}</ref><ref>{{cite journal |last1=Kurbat |first1=N. M. |last2=Praliev |first2=K. D. |last3=Salita |first3=T. A. |last4=Yu |first4=V. K. |last5=Verina |first5=E. L. |title=Neuropharmacological activity of piperidine derivatives (a review) |journal=Pharmaceutical Chemistry Journal |date=July 1991 |volume=25 |issue=7 |pages=450–462 |doi=10.1007/BF00771998}}</ref> '''Pipramadol''' is an ] with potent ] properties.<ref>{{cite journal |last1=Huegi |first1=Bruno S. |last2=Ebnoether |first2=Anton M. |last3=Rissi |first3=Erwin |last4=Gadient |first4=Fulvio |last5=Hauser |first5=Daniel |last6=Roemer |first6=Dietmar |last7=Buescher |first7=Heinz H. |last8=Petcher |first8=Trevor J. |title=Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties |journal=Journal of Medicinal Chemistry |date=January 1983 |volume=26 |issue=1 |pages=42–50 |doi=10.1021/jm00355a010|pmid=6600791 }}</ref><ref>{{cite journal |last1=Kurbat |first1=N. M. |last2=Praliev |first2=K. D. |last3=Salita |first3=T. A. |last4=Yu |first4=V. K. |last5=Verina |first5=E. L. |title=Neuropharmacological activity of piperidine derivatives (a review) |journal=Pharmaceutical Chemistry Journal |date=July 1991 |volume=25 |issue=7 |pages=450–462 |doi=10.1007/BF00771998}}</ref>


==See also== ==See also==
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{{Opioidergics}} {{Opioidergics}}
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Latest revision as of 21:49, 18 December 2024

Pharmaceutical compound
Pipramadol
Clinical data
Other namesFQ 27-096
Identifiers
IUPAC name
  • 2--4-hydroxypiperidin-4-yl]-N-cyclohexyl-N-methylpropanamide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H35ClN2O2
Molar mass407.00 g·mol
3D model (JSmol)
SMILES
  • CC(C(=O)N(C)C1CCCCC1)C2(CCN(CC2)CCC3=CC=CC=C3Cl)O
InChI
  • InChI=1S/C23H35ClN2O2/c1-18(22(27)25(2)20-9-4-3-5-10-20)23(28)13-16-26(17-14-23)15-12-19-8-6-7-11-21(19)24/h6-8,11,18,20,28H,3-5,9-10,12-17H2,1-2H3
  • Key:JRLWHJKUNYBJRC-UHFFFAOYSA-N

Pipramadol is an opioid narcotic with potent analgesic properties.

See also

References

  1. Huegi, Bruno S.; Ebnoether, Anton M.; Rissi, Erwin; Gadient, Fulvio; Hauser, Daniel; Roemer, Dietmar; Buescher, Heinz H.; Petcher, Trevor J. (January 1983). "Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties". Journal of Medicinal Chemistry. 26 (1): 42–50. doi:10.1021/jm00355a010. PMID 6600791.
  2. Kurbat, N. M.; Praliev, K. D.; Salita, T. A.; Yu, V. K.; Verina, E. L. (July 1991). "Neuropharmacological activity of piperidine derivatives (a review)". Pharmaceutical Chemistry Journal. 25 (7): 450–462. doi:10.1007/BF00771998.
Opioid receptor modulators
μ-opioid
(MOR)
Agonists
(abridged;
full list)
Antagonists
δ-opioid
(DOR)
Agonists
Antagonists
κ-opioid
(KOR)
Agonists
Antagonists
Nociceptin
(NOP)
Agonists
Antagonists
Others
  • Others: Kyotorphin (met-enkephalin releaser/degradation stabilizer)
Categories: