Pipramadol: Difference between revisions

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	Pipramadol is an opioid narcotic with potent analgesic properties.<ref> Huegi, Bruno S.; Ebnoether, Anton M.; Rissi, Erwin; Gadient, Fulvio; Hauser, Daniel; Roemer, Dietmar; Buescher, Heinz H.; Petcher, Trevor J. ~~(1983). "~~Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties". Journal of Medicinal Chemistry 26 (1): 42–50. doi:10.1021/jm00355a010.</ref>		'''Pipramadol''' is an ] with potent ] properties.<ref>{{cite journal \|last1=Huegi \|first1=Bruno S. \|last2=Ebnoether \|first2=Anton M. \|last3=Rissi \|first3=Erwin \|last4=Gadient \|first4=Fulvio \|last5=Hauser \|first5=Daniel \|last6=Roemer \|first6=Dietmar \|last7=Buescher \|first7=Heinz H. \|last8=Petcher \|first8=Trevor J. \|title=Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties \|journal=Journal of Medicinal Chemistry \|date=January 1983 \|volume=26 \|issue=1 \|pages=42–50 \|doi=10.1021/jm00355a010}}</ref><ref>{{cite journal \|last1=Kurbat \|first1=N. M. \|last2=Praliev \|first2=K. D. \|last3=Salita \|first3=T. A. \|last4=Yu \|first4=V. K. \|last5=Verina \|first5=E. L. \|title=Neuropharmacological activity of piperidine derivatives (a review) \|journal=Pharmaceutical Chemistry Journal \|date=July 1991 \|volume=25 \|issue=7 \|pages=450–462 \|doi=10.1007/BF00771998}}</ref>

	Review:<ref> Kurbat, N. M.; Praliev, K. D.; Salita, T. A.; Yu, V. K.; Verina, E. L. (1991). "Neuropharmacological activity of piperidine derivatives (a review)". Pharmaceutical Chemistry Journal. 25 (7): 450–462. doi:10.1007/BF00771998.</ref>
	==See also==		==See also==
	*]		*]

	== References ==		== References ==
	{{reflist}}		{{reflist}}

Revision as of 21:42, 18 December 2024

Pharmaceutical compound

Pipramadol
Clinical data

Other names	FQ 27-096
Identifiers
IUPAC name 2--4-hydroxypiperidin-4-yl]-N-cyclohexyl-N-methylpropanamide
ChemSpider	2310156
CompTox Dashboard (EPA)	DTXSID40866480
Chemical and physical data
Formula	C₂₃H₃₅ClN₂O₂
Molar mass	407.00 g·mol
3D model (JSmol)	Interactive image
SMILES CC(C(=O)N(C)C1CCCCC1)C2(CCN(CC2)CCC3=CC=CC=C3Cl)O
InChI InChI=1S/C23H35ClN2O2/c1-18(22(27)25(2)20-9-4-3-5-10-20)23(28)13-16-26(17-14-23)15-12-19-8-6-7-11-21(19)24/h6-8,11,18,20,28H,3-5,9-10,12-17H2,1-2H3 Key:JRLWHJKUNYBJRC-UHFFFAOYSA-N

Pipramadol is an opioid narcotic with potent analgesic properties.

References

Huegi, Bruno S.; Ebnoether, Anton M.; Rissi, Erwin; Gadient, Fulvio; Hauser, Daniel; Roemer, Dietmar; Buescher, Heinz H.; Petcher, Trevor J. (January 1983). "Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties". Journal of Medicinal Chemistry. 26 (1): 42–50. doi:10.1021/jm00355a010.
Kurbat, N. M.; Praliev, K. D.; Salita, T. A.; Yu, V. K.; Verina, E. L. (July 1991). "Neuropharmacological activity of piperidine derivatives (a review)". Pharmaceutical Chemistry Journal. 25 (7): 450–462. doi:10.1007/BF00771998.