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| The activity of boldenone is mainly ], with a low ] potency. Boldenone will increase ] retention, protein synthesis, increases appetite and stimulates the release of ] in the kidneys.<ref>Forbes GB (1985) The effect of anabolic steroids on lean body mass the dose response curve. Metab Clin Exp 34(6) 571–573</ref> Boldenone was synthesized in an attempt to create a long-acting injectable ] (Dianabol), for androgen deficiency disorders. Boldenone acts similar to methandrostenolone with fewer adverse androgenic effects.{{medcn|date=September 2015}} Although commonly compared to ], boldenone lacks progesterone receptor interaction and all the associated ]ic side effects. | The activity of boldenone is mainly ], with a low ] potency. Boldenone will increase ] retention, protein synthesis, increases appetite and stimulates the release of ] in the kidneys.<ref>Forbes GB (1985) The effect of anabolic steroids on lean body mass the dose response curve. Metab Clin Exp 34(6) 571–573</ref> Boldenone was synthesized in an attempt to create a long-acting injectable ] (Dianabol), for androgen deficiency disorders. Boldenone acts similar to methandrostenolone with fewer adverse androgenic effects.{{medcn|date=September 2015}} Although commonly compared to ], boldenone lacks progesterone receptor interaction and all the associated ]ic side effects. | ||
| == |
==Society and culture== | ||
| ===Use in sports=== | |||
| ===Baseball=== | ====Baseball==== | ||
| Boldenone is among the substances ], as well as most other major athletic organizations. ] minor league outfielder Reynaldo Ruiz in September 2010<ref>{{cite news| url=http://mlb.mlb.com/news/article.jsp?ymd=20100930&content_id=15261378&vkey=news_mlb&c_id=mlb | work=MLB.com | title=Three Minor League players suspended | date=September 30, 2010}}</ref> and ] minor league pitcher San Lazaro Solano in January 2011<ref>{{cite news| url=http://mlb.mlb.com/news/article.jsp?ymd=20110120&content_id=16471982&vkey=news_mlb&c_id=mlb | work=MLB.com | title=Phillies Minor League Pitcher San Lazaro Solano Suspended | date=January 20, 2011}}</ref> each received a 50-game suspension for the 2011 season as a result of testing positive for a ] of boldenone. ], formerly of the ], was suspended in July 2015 when he tested positive for boldenone and ], and in February 2016 he again tested positive for boldenone; this marked Mejia's third positive test for a ], for which he received the first PED-related lifetime ban in MLB history.<ref>{{cite news|url=http://espn.go.com/mlb/story/_/id/14768114/jenrry-mejia-new-york-mets-suspended-permanently-mlb-third-positive-ped-test| work=ESPN.com| title=Jenrry Mejia first player to get permanent ban for 3rd positive PED test| date=February 13, 2016}}</ref> Abraham Almonte was suspended for 80 games before the 2016 season after testing positive for boldenone.<ref>{{cite news | url=https://news.yahoo.com/indians-almonte-suspended-80-games-failed-drug-test-000334483--spt.html | work=Yahoo.com| title=Indians' Almonte suspended 80 games for failed drug test| date=February 26, 2016}}</ref> | Boldenone is among the substances ], as well as most other major athletic organizations. ] minor league outfielder Reynaldo Ruiz in September 2010<ref>{{cite news| url=http://mlb.mlb.com/news/article.jsp?ymd=20100930&content_id=15261378&vkey=news_mlb&c_id=mlb | work=MLB.com | title=Three Minor League players suspended | date=September 30, 2010}}</ref> and ] minor league pitcher San Lazaro Solano in January 2011<ref>{{cite news| url=http://mlb.mlb.com/news/article.jsp?ymd=20110120&content_id=16471982&vkey=news_mlb&c_id=mlb | work=MLB.com | title=Phillies Minor League Pitcher San Lazaro Solano Suspended | date=January 20, 2011}}</ref> each received a 50-game suspension for the 2011 season as a result of testing positive for a ] of boldenone. ], formerly of the ], was suspended in July 2015 when he tested positive for boldenone and ], and in February 2016 he again tested positive for boldenone; this marked Mejia's third positive test for a ], for which he received the first PED-related lifetime ban in MLB history.<ref>{{cite news|url=http://espn.go.com/mlb/story/_/id/14768114/jenrry-mejia-new-york-mets-suspended-permanently-mlb-third-positive-ped-test| work=ESPN.com| title=Jenrry Mejia first player to get permanent ban for 3rd positive PED test| date=February 13, 2016}}</ref> Abraham Almonte was suspended for 80 games before the 2016 season after testing positive for boldenone.<ref>{{cite news | url=https://news.yahoo.com/indians-almonte-suspended-80-games-failed-drug-test-000334483--spt.html | work=Yahoo.com| title=Indians' Almonte suspended 80 games for failed drug test| date=February 26, 2016}}</ref> | ||
| ===Mixed martial arts=== | ====Mixed martial arts==== | ||
| ] and ], ] (MMA) fighters from the ] and ], have also tested positive for the banned substance.<ref name="mma1">{{cite web | ] and ], ] (MMA) fighters from the ] and ], have also tested positive for the banned substance.<ref name="mma1">{{cite web | ||
| |url=http://www.mmaweekly.com/absolutenm/templates/dailynews.asp?articleid=2880 | |url=http://www.mmaweekly.com/absolutenm/templates/dailynews.asp?articleid=2880 | ||
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| ] tested positive for boldenone after his July 26, 2008 fight against ] in the ] promotion. Silva was suspended by the ] for a year and fined $2500.<ref>{{cite news|title=Silva, Dewees test positive|url=http://www.sherdog.com/news/news/Silva-Dewees-Test-Positive-14132|accessdate=2017-02-03|work=Sherdog|date=2008-08-21}}</ref> | ] tested positive for boldenone after his July 26, 2008 fight against ] in the ] promotion. Silva was suspended by the ] for a year and fined $2500.<ref>{{cite news|title=Silva, Dewees test positive|url=http://www.sherdog.com/news/news/Silva-Dewees-Test-Positive-14132|accessdate=2017-02-03|work=Sherdog|date=2008-08-21}}</ref> | ||
| ===Australian Football League=== | ====Australian Football League==== | ||
| Justin Charles, a former minor league baseball player with the Florida Marlins, of Richmond FC tested positive for the substance in 1997 and was suspended for 16 matches.<ref>{{cite news|last1=Robinson|first1=Mark|title=Charles kept playing after positive test|url=http://www.heraldsun.com.au/sport/afl/justin-charles-claims-afl-cover-up-in-drug-scandal/story-e6frf9jf-1226082374363|accessdate=2017-02-03|date=2011-06-26}}</ref> | Justin Charles, a former minor league baseball player with the Florida Marlins, of Richmond FC tested positive for the substance in 1997 and was suspended for 16 matches.<ref>{{cite news|last1=Robinson|first1=Mark|title=Charles kept playing after positive test|url=http://www.heraldsun.com.au/sport/afl/justin-charles-claims-afl-cover-up-in-drug-scandal/story-e6frf9jf-1226082374363|accessdate=2017-02-03|date=2011-06-26}}</ref> | ||
| ===Major League Soccer=== | ====Major League Soccer==== | ||
| ] (goal keeper) and ] (defender) of the New York Red Bulls both tested positive for the substance in 2008 and were suspended 10 games and fined 10% of their annual income. They are also the first to abuse MLS drug policy.<ref>{{cite web|title=Conway, Parke banned 10 matches for positive drug tests|url=http://www.espnfc.com/story/582565|website=ESPNFC.com}}</ref> | ] (goal keeper) and ] (defender) of the New York Red Bulls both tested positive for the substance in 2008 and were suspended 10 games and fined 10% of their annual income. They are also the first to abuse MLS drug policy.<ref>{{cite web|title=Conway, Parke banned 10 matches for positive drug tests|url=http://www.espnfc.com/story/582565|website=ESPNFC.com}}</ref> | ||
| ===Horse racing=== | ====Horse racing==== | ||
| Leading horse trainer ] was fined $10,000 after being found guilty on May 15, 2008 of presenting a horse to the races with a prohibited substance in its system. Her horse Perfectly Poised was found to have traces of the banned substance boldenone in its system after finishing second at Canterbury in April 2007.<ref>{{cite news|last1=Pandaram|first1=Jamie|title=Fined $10,000, but Waterhouse claims she's been vindicated - Horseracing - Sport|url=http://www.smh.com.au/news/horseracing/fined-10000-but-waterhouse-claims-shes-been-vindicated/2008/05/15/1210765055503.html|accessdate=2017-02-03|work=www.smh.com.au|date=2008-05-16|language=en}}</ref> | Leading horse trainer ] was fined $10,000 after being found guilty on May 15, 2008 of presenting a horse to the races with a prohibited substance in its system. Her horse Perfectly Poised was found to have traces of the banned substance boldenone in its system after finishing second at Canterbury in April 2007.<ref>{{cite news|last1=Pandaram|first1=Jamie|title=Fined $10,000, but Waterhouse claims she's been vindicated - Horseracing - Sport|url=http://www.smh.com.au/news/horseracing/fined-10000-but-waterhouse-claims-shes-been-vindicated/2008/05/15/1210765055503.html|accessdate=2017-02-03|work=www.smh.com.au|date=2008-05-16|language=en}}</ref> | ||
| ===Brand names=== | |||
| Boldenone is marketed as ] under the following brand names: Boldebal H, Equipoise, and Sybolin.<ref name=names>{{cite web|title=Boldenone international brand names|url=https://www.drugs.com/international/boldenone.html|publisher=Drugs.com|accessdate=28 April 2017}}</ref> It is marketed as a veterinary ] with ] under the brand name Drive.<ref name=names/> | |||
| ==See also== | ==See also== | ||
Revision as of 19:02, 28 April 2017
Not to be confused with 1-Testosterone. Pharmaceutical compound | |
| Clinical data | |
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| AHFS/Drugs.com | International Drug Names |
| Pregnancy category | |
| Routes of administration | Intramuscular |
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| Legal status | |
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| Pharmacokinetic data | |
| Elimination half-life | 14 days |
| Identifiers | |
IUPAC name
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| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.011.533  |
| Chemical and physical data | |
| Formula | C19H26O2 |
| Molar mass | 286.409 g/mol g·mol |
| 3D model (JSmol) | |
| Melting point | 165 °C (329 °F) |
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| (what is this?) (verify) | |
Boldenone (INN, BAN), also known as Δ-testosterone, 1-dehydrotestosterone, or androsta-1,4-dien-3-one-17β-ol, is a synthetic anabolic-androgenic steroid (AAS) and the 1(2)-dehydrogenated analogue of testosterone. Boldenone itself has never been marketed; as a pharmaceutical drug, it is used as boldenone undecylenate, the undecylenate ester.
Effects and side-effects
 | This section does not cite any sources. Please help improve this section by adding citations to reliable sources. Unsourced material may be challenged and removed. (April 2009) (Learn how and when to remove this message) |
The activity of boldenone is mainly anabolic, with a low androgenic potency. Boldenone will increase nitrogen retention, protein synthesis, increases appetite and stimulates the release of erythropoietin in the kidneys. Boldenone was synthesized in an attempt to create a long-acting injectable methandrostenolone (Dianabol), for androgen deficiency disorders. Boldenone acts similar to methandrostenolone with fewer adverse androgenic effects. Although commonly compared to nandrolone, boldenone lacks progesterone receptor interaction and all the associated progestogenic side effects.
Society and culture
Use in sports
Baseball
Boldenone is among the substances banned by Major League Baseball, as well as most other major athletic organizations. Los Angeles Angels minor league outfielder Reynaldo Ruiz in September 2010 and Philadelphia Phillies minor league pitcher San Lazaro Solano in January 2011 each received a 50-game suspension for the 2011 season as a result of testing positive for a metabolite of boldenone. Jenrry Mejia, formerly of the New York Mets, was suspended in July 2015 when he tested positive for boldenone and stanozolol, and in February 2016 he again tested positive for boldenone; this marked Mejia's third positive test for a performance-enhancing drug, for which he received the first PED-related lifetime ban in MLB history. Abraham Almonte was suspended for 80 games before the 2016 season after testing positive for boldenone.
Mixed martial arts
Stephan Bonnar and Josh Barnett, mixed martial arts (MMA) fighters from the UFC and PRIDE Fighting Championships, have also tested positive for the banned substance. After the World Extreme Cagefighting show on January 20, 2006 Muay Thai turned MMA fighter Kit Cope also tested positive for boldenone. Following the Strikeforce card on June 22, 2007 former PRIDE and UFC fighter Phil Baroni tested positive for boldenone, as well as stanozolol. At a K-1 WGP event in Las Vegas on August 17, 2007 two fighters, Rickard Nordstrand and Zabit Samedov, both tested positive for boldenone. Alexandre Franca Nogueira tested positive for boldenone in July 2008.
Antonio Silva tested positive for boldenone after his July 26, 2008 fight against Justin Eilers in the EliteXC promotion. Silva was suspended by the California State Athletic Commission for a year and fined $2500.
Australian Football League
Justin Charles, a former minor league baseball player with the Florida Marlins, of Richmond FC tested positive for the substance in 1997 and was suspended for 16 matches.
Major League Soccer
Jon Conway (goal keeper) and Jeff Parke (defender) of the New York Red Bulls both tested positive for the substance in 2008 and were suspended 10 games and fined 10% of their annual income. They are also the first to abuse MLS drug policy.
Horse racing
Leading horse trainer Gai Waterhouse was fined $10,000 after being found guilty on May 15, 2008 of presenting a horse to the races with a prohibited substance in its system. Her horse Perfectly Poised was found to have traces of the banned substance boldenone in its system after finishing second at Canterbury in April 2007.
Brand names
Boldenone is marketed as veterinary drug under the following brand names: Boldebal H, Equipoise, and Sybolin. It is marketed as a veterinary combination drug with methandriol under the brand name Drive.
See also
- Quinbolone, the 17-cyclopentenyl enol ether of boldenone.
References
- Forbes GB (1985) The effect of anabolic steroids on lean body mass the dose response curve. Metab Clin Exp 34(6) 571–573
- "Three Minor League players suspended". MLB.com. September 30, 2010.
- "Phillies Minor League Pitcher San Lazaro Solano Suspended". MLB.com. January 20, 2011.
- "Jenrry Mejia first player to get permanent ban for 3rd positive PED test". ESPN.com. February 13, 2016.
- "Indians' Almonte suspended 80 games for failed drug test". Yahoo.com. February 26, 2016.
- Ivan Trembow (2006-11-06). "Bonnar Suspended 9 Months for Steroid Use". MMAWeekly.com. Archived from the original on 2009-08-03. Retrieved 2007-07-03.
{{cite web}}: Unknown parameter|deadurl=ignored (|url-status=suggested) (help) - Josh Gross (2007-01-20). "Update: Cope Tests Positive for Steroids". Sherdog.com. Retrieved 2007-07-03.
- Ken Pishna (2007-07-03). "Breaking News: Phil Baroni Tests Positive". MMAWeekly.com. Retrieved 2007-07-03.
- Brent Brookhouse (2007-08-17). "Two More Positive Drug Tests In Fight World". bloodyelbow.com. Archived from the original on September 30, 2007. Retrieved 2007-08-17.
- "Alexandre Nogueira tests positive for boldenone". Sherdog. 2008-07-08. Retrieved 2017-02-03.
- "Silva, Dewees test positive". Sherdog. 2008-08-21. Retrieved 2017-02-03.
- Robinson, Mark (2011-06-26). "Charles kept playing after positive test". Retrieved 2017-02-03.
- "Conway, Parke banned 10 matches for positive drug tests". ESPNFC.com.
- Pandaram, Jamie (2008-05-16). "Fined $10,000, but Waterhouse claims she's been vindicated - Horseracing - Sport". www.smh.com.au. Retrieved 2017-02-03.
- ^ "Boldenone international brand names". Drugs.com. Retrieved 28 April 2017.