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MSD may refer to:

People

• Mahendra Singh Dhoni or MSD (born 1981), Indian cricketer

Companies

• Merck Sharp and Dohme, an international name of Merck & Co., the U.S. and Canada pharmaceutical company formerly related to German Merck KGaA
• MSD Capital, a private investment firm owned by personal computer entrepreneur Michael Dell
• MSD Ignition, a company that specializes in automotive-ignition components; MSD stands for "multiple spark discharge"
• Motor Sports Developments, an automotive-engineering company based in Milton Keynes, United Kingdom; see X25XE

Computers

• Mass storage device, like a USB key
• Memory Stick Duo, a type of solid digital data storage device
• Microsoft Diagnostics, a computer diagnostic program shipped with various versions of DOS and Microsoft Windows operating systems
• Modem Sharing Device
• MSD Super Disk, a floppy-disk drive for Commodore 8-bit systems
• miniSD/microSD

Organizations

Schools and school districts

• Marjory Stoneman Douglas High School, Florida, United States
  • Stoneman Douglas High School shooting
• Marshall School District in Marshall, Arkansas, United States
• Maryland School for the Deaf, United States
• Milford School District, a school district in Milford, Delaware, United States
• Missouri School for the Deaf
• Moscow School District in Moscow, Idaho, United States

Other organizations

• Meclîsa Sûriya Demokratîk or Syrian Democratic Council, the political wing of the Syrian Democratic Forces in Syria
• Metro de Santo Domingo, a rapid-transit system in Santo Domingo, the capital of the Dominican Republic
• Ministry of Social Development (New Zealand)
• Mission Science Division, a group of scientists, research fellows and young graduates working at the European Space Agency
• Mladí sociální demokraté or Young Social Democrats (Czech Republic), a social democratic youth organization in the Czech Republic
• Mladí sociálni demokrati or Young Social Democrats (Slovakia), a social democratic youth organization in Slovakia
• Mobile Security Deployments, the U.S. Diplomatic Security Service's tactical unit
• MSD (Межправительственный совет дорожников) or Intergovernmental Council of Roads, the road authority organisation of the Commonwealth of Independent States

Science and medicine

• Macromolecular Structure Database, one of the services provided by the European Bioinformatics Institute
• Major hypersomnolence disorder
• Marine sanitation device, used in the Regulation of ship pollution in the United States#Marine sanitation devices
• Mars solar date
• Mass spectrometric detector, a type of chromatography detector
• Mean squared displacement, a statistical measure of random motion
• Multiple sulfatase deficiency, a very rare form of metachromatic leukodystrophy
• Musculoskeletal disorders

Other uses

• Magnetic switchable device, a passive magnetic mount that can be activated or deactivated
• Master Scuba Diver, a certification level in recreational scuba diving
• Master of Science in Dentistry, a Dental degree
• Master of Sport Directorship (MSD) at Manchester Metropolitan University
• Mean Shortest Distance, in the context of the PGP Web of trust
• Minimum string distance, the number of insertions, deletions, or substitutions to transform one string into another in Typing#Minimum string distance error rate
• Moorside railway station, England National Rail station code
• Moscow Summer Time
• Most significant digit

• Disambiguation pages