| Revision as of 12:04, 5 December 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,045 edits Saving copy of the {{drugbox}} taken from revid 456801764 of page Phenindione for the Chem/Drugbox validation project (updated: 'DrugBank'). |
Latest revision as of 20:29, 16 July 2024 edit حسن علي البط (talk | contribs)Extended confirmed users, Pending changes reviewers19,940 edits removed Category:Indandiones; added Category:1,3-Indandiones using HotCat |
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{{Short description|Chemical compound}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} |
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{{Drugbox |
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{{Drugbox |
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| verifiedrevid = 464200313 |
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| Verifiedfields = changed |
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| verifiedrevid = 408954109 |
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| IUPAC_name = 2-phenyl-1''H''-indene-1,3(2''H'')-dione |
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| IUPAC_name = 2-phenyl-1''H''-indene-1,3(2''H'')-dione |
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| image = Phenindione.svg |
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| image = Phenindione.svg |
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<!--Clinical data--> |
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<!--Clinical data--> |
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| tradename = |
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| tradename = |
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| legal_status = |
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| legal_status = |
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| routes_of_administration = Oral |
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| routes_of_administration = Oral |
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<!--Pharmacokinetic data--> |
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<!--Pharmacokinetic data--> |
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| bioavailability = |
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| bioavailability = |
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| elimination_half-life = 5 to 10 hours |
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| elimination_half-life = 5 to 10 hours |
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| excretion = |
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| excretion = |
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<!--Identifiers--> |
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<!--Identifiers--> |
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| IUPHAR_ligand = 6838 |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 83-12-5 |
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| CAS_number = 83-12-5 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D08354 |
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| KEGG = D08354 |
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| ChEBI_Ref = {{ebicite|changed|EBI}} |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| ChEBI = 8066 |
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| ChEBI = 8066 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 711 |
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| ChEMBL = 711 |
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<!--Chemical data--> |
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<!--Chemical data--> |
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| C=15 | H=10 | O=2 |
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| C=15 | H=10 | O=2 |
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| molecular_weight = 222.239 g/mol |
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| smiles = O=C2c1ccccc1C(=O)C2c3ccccc3 |
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| smiles = O=C2c1ccccc1C(=O)C2c3ccccc3 |
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| InChI = 1/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H |
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| InChIKey = NFBAXHOPROOJAW-UHFFFAOYAZ |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H |
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| StdInChI = 1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H |
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| StdInChIKey = NFBAXHOPROOJAW-UHFFFAOYSA-N |
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| StdInChIKey = NFBAXHOPROOJAW-UHFFFAOYSA-N |
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}} |
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}} |
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'''Phenindione''' is an ] which functions as a ]. |
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Phenindione was introduced in the early 1950s. It acts similar to ], but it has been associated with hypersensitivity reactions, so it is rarely used and warfarin is preferred.<ref name="pmid15743920">{{cite journal | vauthors = Naisbitt DJ, Farrell J, Chamberlain PJ, Hopkins JE, Berry NG, Pirmohamed M, Park BK | title = Characterization of the T-cell response in a patient with phenindione hypersensitivity | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 313 | issue = 3 | pages = 1058–65 | date = June 2005 | pmid = 15743920 | doi = 10.1124/jpet.105.083758 | s2cid = 17052792 }}</ref><ref>{{cite book | veditors = Sweetman SC |year=2009 | title=Martindale: The Complete Drug Reference |edition=36th |publisher=Pharmaceutical Press| location=London |at="Phenindione", p. 1369}}</ref> |
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== References == |
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{{reflist}} |
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== External links == |
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* {{DiseasesDB|30536}} |
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{{Antithrombotics}} |
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] |
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] |
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{{blood-drug-stub}} |