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AGR3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3PH9
Identifiers
Aliases	AGR3, AG3, BCMP11, HAG3, PDIA18, hAG-3, AG-3, anterior gradient 3, protein disulphide isomerase family member
External IDs	OMIM: 609482; MGI: 2685734; HomoloGene: 45551; GeneCards: AGR3; OMA:AGR3 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) Band 7p21.1 Start 16,859,412 bp End 16,881,987 bp
Gene location (Mouse) Chr. Chromosome 12 (mouse) Band 12|12 A3 Start 35,975,619 bp End 35,999,735 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bronchial epithelial cell mucosa of ileum mucosa of sigmoid colon right uterine tube rectum jejunal mucosa mucosa of transverse colon pancreatic epithelial cell duodenum trachea Top expressed in saccule vestibular sensory epithelium utricle olfactory epithelium primary oocyte zygote secondary oocyte right lung lobe trachea cochlea More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding dystroglycan binding Cellular component endoplasmic reticulum cellular component intracellular membrane-bounded organelle Biological process cell differentiation negative regulation of cell death biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 155465 403205 Ensembl ENSG00000173467 ENSMUSG00000036231 UniProt Q8TD06 Q8R3W7 RefSeq (mRNA) NM_176813 NM_207531 RefSeq (protein) NP_789783 NP_997414 Location (UCSC) Chr 7: 16.86 – 16.88 Mb Chr 12: 35.98 – 36 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Anterior gradient protein 3 homolog is a protein that in humans is encoded by the AGR3 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000173467 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000036231 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Fletcher GC, Patel S, Tyson K, Adam PJ, Schenker M, Loader JA, Daviet L, Legrain P, Parekh R, Harris AL, Terrett JA (Feb 2003). "hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan". British Journal of Cancer. 88 (4): 579–85. doi:10.1038/sj.bjc.6600740. PMC 2377166. PMID 12592373.
6. Adam PJ, Boyd R, Tyson KL, Fletcher GC, Stamps A, Hudson L, Poyser HR, Redpath N, Griffiths M, Steers G, Harris AL, Patel S, Berry J, Loader JA, Townsend RR, Daviet L, Legrain P, Parekh R, Terrett JA (Feb 2003). "Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer". The Journal of Biological Chemistry. 278 (8): 6482–9. doi:10.1074/jbc.M210184200. PMID 12477722.
7. "Entrez Gene: AGR3 anterior gradient homolog 3 (Xenopus laevis)".

External links

• Human AGR3 genome location and AGR3 gene details page in the UCSC Genome Browser.

Further reading

• Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Zhang Z, Henzel WJ (Oct 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Science. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
• Persson S, Rosenquist M, Knoblach B, Khosravi-Far R, Sommarin M, Michalak M (Sep 2005). "Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family". Molecular Phylogenetics and Evolution. 36 (3): 734–40. doi:10.1016/j.ympev.2005.04.002. PMID 15935701.

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• Endoplasmic reticulum resident proteins