| Alpha-humulene 10-hydroxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.150 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Alpha-humulene 10-hydroxylase (EC 1.14.13.150, CYP71BA1) is an enzyme with systematic name alpha-humulene,NADPH:oxygen 10-oxidoreductase. This enzyme catalyses the following chemical reaction
- alpha-humulene + O2 + NADPH + H 10-hydroxy-alpha-humulene + NADP + H2O
10-hydroxy-alpha-humulene + NADP + H2OAlpha-humulene 10-hydroxylase requires cytochrome P-450.
References
- Yu F, Okamoto S, Harada H, Yamasaki K, Misawa N, Utsumi R (March 2011). "Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis". Cellular and Molecular Life Sciences. 68 (6): 1033–40. doi:10.1007/s00018-010-0506-4. PMC 11114803. PMID 20730551. S2CID 35653829.
External links
- Alpha-humulene+10-hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
| Oxidoreductases: dioxygenases, including steroid hydroxylases (EC 1.14) | |
|---|---|
| 1.14.11: 2-oxoglutarate | |
| 1.14.13: NADH or NADPH | |
| 1.14.14: reduced flavin or flavoprotein | |
| 1.14.15: reduced iron–sulfur protein | |
| 1.14.16: reduced pteridine (BH4 dependent) | |
| 1.14.17: reduced ascorbate | |
| 1.14.18-19: other | |
| 1.14.99 - miscellaneous | |
| Enzymes | |
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| Activity | |
| Regulation | |
| Classification | |
| Kinetics | |
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