Misplaced Pages

Altizide

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Altizide
Names
IUPAC name (3R)-3--6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Other names
  • Althiazide
  • CB 8093
  • P 1779
  • Altizidum
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.024.541 Edit this at Wikidata
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)/t11-/m1/s1Key: VGLGVJVUHYTIIU-LLVKDONJSA-N
  • InChI=1/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)/t11-/m1/s1Key: VGLGVJVUHYTIIU-LLVKDONJBT
SMILES
  • O=S(=O)(c1c(Cl)cc2c(c1)S(=O)(=O)N(N2)CSC\C=C)N
  • C=CCSCC1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
Properties
Chemical formula C11H14ClN3O4S3
Molar mass 383.89456
Density 1.502 g/mL
Boiling point 625.8 °C (1,158.4 °F; 898.9 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

Altizide is a thiazide diuretic. In combination with spironolactone it is sold under the brand name of Aldactacine and Aldactazine by Pfizer and other names by other companies.

References

  1. "Altizide". drugs.com.
  2. Dueymes, J. M (1990). "Clinical update: spironolactone and altizide as monotherapy in systemic hypertension". The American Journal of Cardiology. 65 (23): 20K – 23K. doi:10.1016/0002-9149(90)91272-8. PMID 2191585.
Diuretics (C03)
Sulfonamides
(and etacrynic acid)
CA inhibitors (at PT)
Loop (Na-K-Cl at AL)
Thiazides (Na-Cl at DCT,
Calcium-sparing)
Thiazide-likes (primarily DCT)
Potassium-sparing (at CD)
ESC blockers
Aldosterone antagonists
Osmotic diuretics (PT, DL)
Vasopressin receptor inhibitors
(DCT and CD)
Other
Combination products


Stub icon

This drug article relating to the cardiovascular system is a stub. You can help Misplaced Pages by expanding it.

Categories: