Ancrum is a surname. Notable people with the surname include:
- David Ancrum (born 1958), American retired professional and college basketball player
- Marion Ancrum (fl. 1885–1919), Scottish watercolour artist
- William Ancrum (c. 1722 – 1808), American merchant and indigo planter
See also
- Ancrum, a village in the Borders area of Scotland
- Ancrum House, a 1920s mansion (demolished in 1963), famous for its formal gardens, in New York state
- Earl of Ancrum, a subsidiary title of the Marquess of Lothian in the Peerage of Scotland
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