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Aspoxicillin

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Chemical compound

Pharmaceutical compound
Aspoxicillin
Clinical data
Trade namesDoyle
Other namesTA-058
Identifiers
IUPAC name
  • (2S,5R,6R)-6-amino]-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicycloheptane-2-carboxylic acid
CAS Number
PubChem CID
DrugBank
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.162.655 Edit this at Wikidata
Chemical and physical data
FormulaC21H27N5O7S
Molar mass493.54 g·mol

Aspoxicillin (trade name Doyle) is an antibiotic drug of the beta-lactam class. It is an injectable form of penicillin that is highly active against Gram-positive and Gram-negative bacteria, including Bacillus fragilis, which is resistant to other beta-lactam antibiotics. It is approved for use in Japan.

References

  1. ^ "Aspoxicillin". IUPHAR/BPS Guide to Pharmacology.
  2. Matsumoto K (July 1987). "". The Japanese Journal of Antibiotics. 40 (7): 1221–1242. PMID 3316732.
  3. "Aspoxicillin". Inxight Drugs. National Center for Advancing Translational Sciences.
  4. Edwards R (December 1997). "Resistance to beta-lactam antibiotics in Bacteroides spp". Journal of Medical Microbiology. 46 (12): 979–986. doi:10.1099/00222615-46-12-979. PMID 9402919.
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