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CMP-N-acylneuraminate phosphodiesterase

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Enzyme
CMP-N-acylneuraminate phosphodiesterase
Identifiers
EC no.3.1.4.40
CAS no.55326-41-5
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The enzyme CMP-N-acylneuraminate phosphodiesterase (EC 3.1.4.40) catalyzes the reaction

CMP-N-acylneuraminate + H2O {\displaystyle \rightleftharpoons } CMP + N-acylneuraminate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is CMP-N-acylneuraminate N-acylneuraminohydrolase. Other names in common use include CMP-sialate hydrolase, CMP-sialic acid hydrolase, CMP-N-acylneuraminic acid hydrolase, cytidine monophosphosialic hydrolase, cytidine monophosphosialate hydrolase, cytidine monophosphate-N-acetylneuraminic acid hydrolase, and CMP-N-acetylneuraminate hydrolase.

References

  • Kean EL, Bighouse KJ (1974). "Cytidine 5′-monophosphosialic acid hydrolase. Subcellular location and properties". J. Biol. Chem. 249 (24): 7813–23. PMID 4372219.
Hydrolase: esterases (EC 3.1)
3.1.1: Carboxylic
ester hydrolases
3.1.2: Thioesterase
3.1.3: Phosphatase
3.1.4:
Phosphodiesterase
3.1.6: Sulfatase
Nuclease (includes
deoxyribonuclease
and ribonuclease)
3.1.11-16:
Exonuclease
Exodeoxyribonuclease
Exoribonuclease
3.1.21-31:
Endonuclease
Endodeoxyribonuclease
Endoribonuclease
either deoxy- or ribo-    
Enzymes
Activity
Regulation
Classification
Kinetics
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