Charles Stone may refer to:
- Sir Charles Stone (mayor) (1850–1931), mayor of Greenwich, England, 1915–1920
- Charles Stone III (born 1966), American film director, son of Chuck Stone
- Charles A. Stone (1867-1941), American electrical engineer and co-founder of Stone & Webster
- Charles B. Stone III (1904–1992), United States Air Force general
- Charles D. Stone (1920–1992), Pennsylvania politician
- Charles Edwin Stone (1889–1952), English recipient of the Victoria Cross
- Gordon Stone (rugby union) (Charles Gordon Stone, 1914–2015), Australian rugby union player
- Charles Joel Stone (1936–2019), American statistician and mathematician
- Charles P. Stone (1915–2012), American major general and commander of the 4th Infantry Division in the Vietnam War
- Charles Pomeroy Stone (1824–1887), Union general during the American Civil War
- Charles Warren Stone (1843–1912), United States Representative from and Lieutenant Governor of Pennsylvania
- Charles Stone (English cricketer) (1865–1951), English cricketer
- Charles Stone (New Zealand cricketer) (1866–1903), New Zealand cricketer
- Charlie Stone, a fictional character in the TV series Veronica Mars
- Chuck Stone (1924–2014), American journalist and Tuskegee Airman
- Charlie Stone (rugby league) (1950–2018), English rugby league player
- Charles Stone (priest) (died 1799), Anglican priest in Ireland
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