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COL21A1
Identifiers
Aliases	COL21A1, collagen, type XXI, alpha 1, COLA1L, dJ682J15.1, dJ708F5.1, FP633, collagen type XXI alpha 1, collagen type XXI alpha 1 chain
External IDs	OMIM: 610002; HomoloGene: 49949; GeneCards: COL21A1; OMA:COL21A1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p12.1|6p12.3-p11.2 Start 56,056,590 bp End 56,394,094 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bronchial epithelial cell sural nerve Descending thoracic aorta ascending aorta myocardium of left ventricle right coronary artery skin of hip periodontal fiber seminal vesicula left coronary artery n/a More reference expression data BioGPS n/a
Gene ontology Molecular function extracellular matrix structural constituent conferring tensile strength Cellular component cytoplasm extracellular matrix extracellular region collagen endoplasmic reticulum lumen cytosol extracellular space collagen-containing extracellular matrix Biological process growth plate cartilage chondrocyte morphogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81578 n/a Ensembl ENSG00000124749 n/a UniProt Q96P44 n/a RefSeq (mRNA) NM_030820 NM_001318751 NM_001318752 NM_001318753 NM_001318754 n/a RefSeq (protein) NP_001305680 NP_001305681 NP_001305682 NP_001305683 NP_110447 n/a Location (UCSC) Chr 6: 56.06 – 56.39 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Collagen alpha-1(XXI) chain is a protein that in humans is encoded by the COL21A1 gene. The protein is an extracellular matrix component of blood vessel walls, secreted by smooth-muscle cells. The protein may contribute to the extracellular matrix assembly of the vascular network during blood vessel formation.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000124749 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "COL21A1 collagen, type XXI, alpha 1". Entrez Gene: COL21A1. United States National Center for Biotechnology Information.
4. Chou MY, Li HC (March 2002). "Genomic organization and characterization of the human type XXI collagen (COL21A1) gene". Genomics. 79 (3): 395–401. doi:10.1006/geno.2002.6712. PMID 11863369.

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