George Ryan (born 1934) is an American politician, governor of Illinois, 1999–2003.
George Ryan may also refer to:
- George Ryan (Irish-Danish businessman) (1783 or 1785 –1865), Danish businessman and plantation owner
- George Ryan (Canadian politician) (1806–1876), member of the Canadian House of Commons
- Sir George Ryan (Antiguan businessman) (born 1934), Antiguan businessperson
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