HCO may refer to:
In arts and entertainment
In science and technology
- Aldehyde (HCO-)
- Harvard College Observatory
- Hearing carry over, a type of telecommunications relay service
- Heliocentric orbit, an orbit around the Sun
- Holocene climatic optimum
Businesses and organizations
- Handball Club Odense, a Danish handball club
- Hans Christian Ørsted Institute (HCØ)
- Hollister Co., an American lifestyle brand
- National Socialist Society (Russian: Национал-социалистическое общество, НСО)
- Hanwell Community Observatory, a public outreach astronomy organisation; see Hanwell, Oxfordshire
- Hubbard Communications Office, an organization in the Church of Scientology
- Health Care Organization
Other
- The Hong Kong High Court Ordinance.
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