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Hydroquinone 1,2-dioxygenase (EC 1.13.11.66, hydroquinone dioxygenase) is an enzyme with systematic name benzene-1,4-diol:oxygen 1,2-oxidoreductase (decyclizing). This enzyme catalyses the following chemical reaction

benzene-1,4-diol + O₂ ${\displaystyle \rightleftharpoons }$ (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoate

The enzyme is an extradiol-type dioxygenase. It belongs to the nonheme-iron(II)-dependent dioxygenase family.

References

1. Miyauchi K, Adachi Y, Nagata Y, Takagi M (November 1999). "Cloning and sequencing of a novel meta-cleavage dioxygenase gene whose product is involved in degradation of gamma-hexachlorocyclohexane in Sphingomonas paucimobilis". Journal of Bacteriology. 181 (21): 6712–9. PMC 94136. PMID 10542173.
2. Moonen MJ, Synowsky SA, van den Berg WA, Westphal AH, Heck AJ, van den Heuvel RH, Fraaije MW, van Berkel WJ (August 2008). "Hydroquinone dioxygenase from pseudomonas fluorescens ACB: a novel member of the family of nonheme-iron(II)-dependent dioxygenases". Journal of Bacteriology. 190 (15): 5199–209. doi:10.1128/JB.01945-07. PMC 2493252. PMID 18502867.
3. Shen W, Liu W, Zhang J, Tao J, Deng H, Cao H, Cui Z (October 2010). "Cloning and characterization of a gene cluster involved in the catabolism of p-nitrophenol from Pseudomonas putida DLL-E4". Bioresource Technology. 101 (19): 7516–22. doi:10.1016/j.biortech.2010.04.052. PMID 20466541.

External links

• Hydroquinone+1,2-dioxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

• Biology

• EC 1.13.11