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KRT32
Identifiers
Aliases	KRT32, HA2, HKA2, KRTHA2, hHa2, keratin 32
External IDs	OMIM: 602760; MGI: 1309995; HomoloGene: 68246; GeneCards: KRT32; OMA:KRT32 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q21.2 Start 41,459,513 bp End 41,467,386 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11 D|11 63.4 cM Start 99,971,674 bp End 99,979,052 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in hair follicle skin of arm periodontal fiber nipple human penis skin of abdomen skin of leg vagina pharynx cervix Top expressed in lip esophagus superior surface of tongue hair follicle Ileal epithelium skin of back morula urethra skin of abdomen extensor digitorum longus muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural molecule activity Cellular component intermediate filament extracellular exosome cytosol Biological process epidermis development keratinization cornification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3882 16670 Ensembl ENSG00000108759 ENSMUSG00000046095 UniProt Q14532 Q62168 RefSeq (mRNA) NM_002278 NM_001159374 NM_010665 RefSeq (protein) NP_002269 NP_001152846 Location (UCSC) Chr 17: 41.46 – 41.47 Mb Chr 11: 99.97 – 99.98 Mb PubMed search
Wikidata
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Keratin, type I cuticular Ha2 is a protein that in humans is encoded by the KRT32 gene.

The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q21.2 and have the same direction of transcription.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000108759 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000046095 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Rogers MA, Nischt R, Korge B, Krieg T, Fink TM, Lichter P, Winter H, Schweizer J (Nov 1995). "Sequence data and chromosomal localization of human type I and type II hair keratin genes". Exp Cell Res. 220 (2): 357–62. doi:10.1006/excr.1995.1326. PMID 7556444.
6. Rogers MA, Winter H, Langbein L, Krieg T, Schweizer J (Dec 1996). "Genomic characterization of the human type I cuticular hair keratin hHa2 and identification of an adjacent novel type I hair keratin gene hHa5". J Invest Dermatol. 107 (4): 633–8. doi:10.1111/1523-1747.ep12584243. PMID 8823373.
7. Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
8. ^ "Entrez Gene: KRT32 keratin 32".

Further reading

• Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins". J. Invest. Dermatol. 101 (1 Suppl): 56S – 59S. doi:10.1111/1523-1747.ep12362635. PMID 7686952.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Adkins JN, Varnum SM, Auberry KJ, et al. (2003). "Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry". Mol. Cell. Proteomics. 1 (12): 947–55. doi:10.1074/mcp.M200066-MCP200. PMID 12543931.
• Langbein L, Rogers MA, Winter H, et al. (1999). "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle". J. Biol. Chem. 274 (28): 19874–84. doi:10.1074/jbc.274.28.19874. PMID 10391933.
• Heid HW, Moll I, Franke WW (1988). "Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles". Differentiation. 37 (2): 137–57. doi:10.1111/j.1432-0436.1988.tb00805.x. PMID 2456239.

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