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A ketosamine is a combination of two organic chemistry functional groups, ketose and amine. An example is the family of fructosamines which are recognized by fructosamine-3-kinase, which may trigger the degradation of advanced glycation end-products (though the true clinical significance of this pathway is unclear). Fructosamine itself, the specific compound 1-amino-1-deoxy-D-fructose (isoglucosamine), was first synthesized by Nobel laureate Hermann Emil Fischer in 1886.
References
- Hakomori, Sen-itiroh; Ishimoda, Taiko (1962). "Purification and Characterization of Urinary Glycopeptides Containing N-Peptidyl-1-Ketosamine Structure". The Journal of Biochemistry. 52 (4): 250–260. doi:10.1093/oxfordjournals.jbchem.a127609.
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