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L-glycol dehydrogenase

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L-glycol dehydrogenase
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EC no.1.1.1.185
CAS no.77967-75-0
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In enzymology, a L-glycol dehydrogenase (EC 1.1.1.185) is an enzyme that catalyzes the chemical reaction

an L-glycol + NAD(P) {\displaystyle \rightleftharpoons } a 2-hydroxycarbonyl compound + NAD(P)H + H

The 3 substrates of this enzyme are L-glycol, NAD, and NADP, whereas its 4 products are 2-hydroxycarbonyl compound, NADH, NADPH, and H.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is L-glycol:NAD(P) oxidoreductase. Other names in common use include glycol (nicotinamide adenine dinucleotide (phosphate)), dehydrogenase, L-(+)-glycol:NAD(P) oxidoreductase, and L-glycol:NAD(P) dehydrogenase.

References

  • Bernardo A, Burgos J, Martin R (1981). "Purification and some properties of L-glycol dehydrogenase from hen's muscle". Biochim. Biophys. Acta. 659 (1): 189–98. doi:10.1016/0005-2744(81)90283-7. PMID 7018582.
Oxidoreductases: alcohol oxidoreductases (EC 1.1)
1.1.1: NAD/NADP acceptor
1.1.2: cytochrome acceptor
1.1.3: oxygen acceptor
1.1.4: disulfide as acceptor
1.1.5: quinone/similar acceptor
1.1.99: other acceptors
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