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The Lachnospiraceae are a family of obligately anaerobic, variably spore-forming bacteria in the order Eubacteriales that ferment diverse plant polysaccharides to short-chain fatty acids (butyrate, acetate) and alcohols (ethanol). These bacteria are among the most abundant taxa in the rumen and the human gut microbiota. Members of this family may protect against colon cancer in humans by producing butyric acid. Lachnospiraceae have been found to contribute to diabetes in genetically susceptible (ob/ob) germ-free mice.

References

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11. Boutard, M; Cerisy, T (13 November 2014). "Functional Diversity of Carbohydrate-Active Enzymes Enabling a Bacterium to Ferment Plant Biomass". PLOS Genetics. 10 (11): e1004773. doi:10.1371/journal.pgen.1004773. PMC 4230839. PMID 25393313.
12. Seshadri, R; Leahy, SC (19 March 2018). "Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection". Nature Biotechnology. 36 (4): 359–367. doi:10.1038/nbt.4110. PMC 6118326. PMID 29553575.
13. Phyllis Kanki; Darrell Jay Grimes, eds. (2013). Infectious diseases selected entries from the Encyclopedia of sustainability science and technology. New York: Springer. ISBN 978-1-4614-5719-0.
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15. Paul De Vos; et al., eds. (2009). Bergey's manual of systematic bacteriology (2nd ed.). Dordrecht: Springer. ISBN 978-0-387-68489-5.
16. Meehan, C. J.; Beiko, R. G. (12 March 2014). "A Phylogenomic View of Ecological Specialization in the Lachnospiraceae, a Family of Digestive Tract-Associated Bacteria". Genome Biology and Evolution. 6 (3): 703–713. doi:10.1093/gbe/evu050. PMC 3971600. PMID 24625961.
17. Xia, Li C.; Liu, Gang; Gao, Yingxin; Li, Xiaoxin; Pan, Hongfei; Ai, Dongmei (2019). "Identifying Gut Microbiota Associated With Colorectal Cancer Using a Zero-Inflated Lognormal Model". Frontiers in Microbiology. 10: 826. doi:10.3389/fmicb.2019.00826. ISSN 1664-302X. PMC 6491826. PMID 31068913.
18. Kameyama, Keishi; Itoh, Kikuji (2014). "Intestinal Colonization by a Lachnospiraceae Bacterium Contributes to the Development of Diabetes in Obese Mice". Microbes and Environments. 29 (4): 427–430. doi:10.1264/jsme2.ME14054. ISSN 1342-6311. PMC 4262368. PMID 25283478.

Further reading

• Newton, R. J.; VandeWalle, J. L.; Borchardt, M. A.; Gorelick, M. H.; McLellan, S. L. (29 July 2011). "Lachnospiraceae and Bacteroidales Alternative Fecal Indicators Reveal Chronic Human Sewage Contamination in an Urban Harbor". Applied and Environmental Microbiology. 77 (19): 6972–6981. Bibcode:2011ApEnM..77.6972N. doi:10.1128/AEM.05480-11. PMC 3187108. PMID 21803887.
• Kameyama, Keishi; Itoh, Kikuji (2014). "Intestinal Colonization by a Lachnospiraceae Bacterium Contributes to the Development of Diabetes in Obese Mice". Microbes and Environments. 29 (4): 427–430. doi:10.1264/jsme2.ME14054. PMC 4262368. PMID 25283478.
• Paul De Vos; et al., eds. (2009). Bergey's manual of systematic bacteriology (2nd ed.). Dordrecht: Springer. ISBN 978-0-387-68489-5.
• Almeida, edited by Susan S. Cho, Nelson (2012). Dietary fiber and health. Boca Raton: CRC Press. ISBN 978-1-4398-9929-8. {{cite book}}: |first1= has generic name (help)CS1 maint: multiple names: authors list (link)
• Olsen, LeighAnne; Choffnes, Eileen R.; Academies, Alison Mack, rapporteurs ; Forum on Microbial Threats, Board on Global Health, Institute of Medicine of the National (2012). The social biology of microbial communities : workshop summary. Washington, D.C.: National Academies Press. ISBN 978-0-309-26432-7.{{cite book}}: CS1 maint: multiple names: authors list (link)
• Nelson, Karen E.; Peterson, editor ; foreword by Jane L.; Garges, Susan (2011). Metagenomics of the human body. New York: Springer. ISBN 978-1-4419-7089-3. {{cite book}}: |first2= has generic name (help)CS1 maint: multiple names: authors list (link)

• Lachnospiraceae
• Bacteria families