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Nandrolone furylpropionate

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Chemical compound Pharmaceutical compound
Nandrolone furylpropionate
Clinical data
Trade namesDemelon
Other namesNFP; Nandrolone 17β-furylpropionate; 19-Nortestosterone 17β-(2-furanyl)propanoate
Routes of
administration
Intramuscular injection
Drug classAndrogen; Anabolic steroid; Androgen ester; Progestogen
Identifiers
IUPAC name
  • phenanthren-17-yl] 3-(furan-2-yl)propanoate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.028.709 Edit this at Wikidata
Chemical and physical data
FormulaC25H32O4
Molar mass396.527 g·mol
3D model (JSmol)
SMILES
  • C12CC3(1CC2OC(=O)CCC4=CC=CO4)CCC5=CC(=O)CC35
InChI
  • InChI=1S/C25H32O4/c1-25-13-12-20-19-8-5-17(26)15-16(19)4-7-21(20)22(25)9-10-23(25)29-24(27)11-6-18-3-2-14-28-18/h2-3,14-15,19-23H,4-13H2,1H3/t19-,20+,21+,22-,23-,25-/m0/s1
  • Key:ICNIVTHKZKRHPD-YNFNDHOQSA-N

Nandrolone furylpropionate (NFP) (JANTooltip Japanese Accepted Name) (brand name Demelon), also known as 19-nortestosterone 17β-(2-furanyl)propanoate, is a synthetic androgen and anabolic steroid and a nandrolone ester. It was developed and marketed by Mochida Pharmaceutical in Japan in the 1960s.

Relative affinities (%) of nandrolone and related steroids
Compound PRTooltip Progesterone receptor ARTooltip Androgen receptor ERTooltip Estrogen receptor GRTooltip Glucocorticoid receptor MRTooltip Mineralocorticoid receptor SHBGTooltip Sex hormone-binding globulin CBGTooltip Corticosteroid-binding globulin
Nandrolone 20 154–155 <0.1 0.5 1.6 1–16 0.1
Testosterone 1.0–1.2 100 <0.1 0.17 0.9 19–82 3–8
Estradiol 2.6 7.9 100 0.6 0.13 8.7–12 <0.1
Notes: Values are percentages (%). Reference ligands (100%) were progesterone for the PRTooltip progesterone receptor, testosterone for the ARTooltip androgen receptor, estradiol for the ERTooltip estrogen receptor, dexamethasone for the GRTooltip glucocorticoid receptor, aldosterone for the MRTooltip mineralocorticoid receptor, dihydrotestosterone for SHBGTooltip sex hormone-binding globulin, and cortisol for CBGTooltip corticosteroid-binding globulin. Sources: See template.

See also

References

  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 660–. ISBN 978-1-4757-2085-3.
  2. Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 716–717. ISBN 978-3-88763-075-1.
  3. Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. ISBN 978-94-011-4439-1.
  4. The Bulletin of Tokyo Medical and Dental University. Tokyo Medical and Dental University. 1965. pp. 342, 344.
  5. Ishibashi T (1969). The Oriental Economist. Oriental Economist. p. 36.


Androgens and antiandrogens
Androgens
(incl. AASTooltip anabolic–androgenic steroid)
ARTooltip Androgen receptor agonists
Progonadotropins
Antiandrogens
ARTooltip Androgen receptor antagonists
Steroidogenesis
inhibitors
5α-Reductase
Others
Antigonadotropins
Others
See also
Androgen receptor modulators
Estrogens and antiestrogens
Progestogens and antiprogestogens
List of androgens/anabolic steroids
Progestogens and antiprogestogens
Progestogens
(and progestins)
PRTooltip Progesterone receptor agonists
Antiprogestogens
SPRMsTooltip Selective progesterone receptor modulators
PRTooltip Progesterone receptor antagonists
See also
Progesterone receptor modulators
Androgens and antiandrogens
Estrogens and antiestrogens
List of progestogens
Androgen receptor modulators
ARTooltip Androgen receptor
Agonists
SARMsTooltip Selective androgen receptor modulator
Antagonists
GPRC6A
Agonists
See also
Receptor/signaling modulators
Androgens and antiandrogens
Estrogen receptor modulators
Progesterone receptor modulators
List of androgens and anabolic steroids
Progesterone receptor modulators
PRTooltip Progesterone receptor
Agonists
Mixed
(SPRMsTooltip Selective progesterone receptor modulators)
Antagonists
mPRTooltip Membrane progesterone receptor
(PAQRTooltip Progestin and adipoQ receptor)
Agonists
Antagonists
See also
Receptor/signaling modulators
Progestogens and antiprogestogens
Androgen receptor modulators
Estrogen receptor modulators
List of progestogens


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