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Zofenoprilat

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Zofenoprilat
Names
IUPAC name (4S)-N--4-(phenylsulfanyl)-L-proline
Systematic IUPAC name (2S,4S)-1--4-(phenylsulfanyl)pyrrolidine-2-carboxylic acid
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C15H19NO3S2/c1-10(9-20)14(17)16-8-12(7-13(16)15(18)19)21-11-5-3-2-4-6-11/h2-6,10,12-13,20H,7-9H2,1H3,(H,18,19)/t10-,12-,13-/m0/s1Key: UQWLOWFDKAFKAP-DRZSPHRISA-N
  • InChI=1/C15H19NO3S2/c1-10(9-20)14(17)16-8-12(7-13(16)15(18)19)21-11-5-3-2-4-6-11/h2-6,10,12-13,20H,7-9H2,1H3,(H,18,19)/t10-,12-,13-/m0/s1Key: UQWLOWFDKAFKAP-DRZSPHRIBV
SMILES
  • C(CS)C(=O)N1C(C1C(O)=O)SC1=CC=CC=C1
Properties
Chemical formula C15H19NO3S2
Molar mass 325.44 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound
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Find sources: "Zofenoprilat" – news · newspapers · books · scholar · JSTOR (October 2022)

Zofenoprilat is an angiotensin-converting enzyme inhibitor, and is the free sulfhydryl active metabolite of zofenopril.

References

  1. Subissi, A; Evangelista, S; Giachetti, A (1999). "Preclinical Profile of Zofenopril: An Angiotensin Converting Enzyme Inhibitor with Peculiar Cardioprotective Properties". Cardiovascular Drug Reviews. 17 (2): 115. doi:10.1111/j.1527-3466.1999.tb00008.x.
Angiotensin receptor modulators
ATRTooltip Angiotensin receptor
Combinations:


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