Misplaced Pages

Butamisole: Difference between revisions

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Browse history interactivelyNext edit →Content deleted Content addedVisualWikitext
Revision as of 13:49, 24 December 2024 editInnerstream (talk | contribs)Autopatrolled, Extended confirmed users4,114 edits new page  Revision as of 13:49, 24 December 2024 edit undoCitation bot (talk | contribs)Bots5,450,102 edits Altered pages. Add: pmid, pages, issue, volume, journal, date, title, authors 1-1. Formatted dashes. | Use this bot. Report bugs. | Suggested by Innerstream | #UCB_webformNext edit →
Line 57: Line 57:
}} }}


'''Butamisole''' is a pharmaceutical drug used in veterinary medicine.<ref>{{cite journal | title = The efficacy and safety of injectable butamisole in dogs | journal = Veterinary Medicine & Small Animal Clinician | date = 1979 | volume = 74 | issue = 4 | pages = 487-495 | '''Butamisole''' is a pharmaceutical drug used in veterinary medicine.<ref>{{cite journal | title = The efficacy and safety of injectable butamisole in dogs | journal = Veterinary Medicine & Small Animal Clinician | date = 1979 | volume = 74 | issue = 4 | pages = 487–495 |
author = B. T. Alford, G. T. Wang, T. R. Garces, R. B. Dougherty, R. E. Bradley }}</ref> It is an ] of the ] class.<ref>{{Cite journal | doi = 10.1016/S1090-0233(05)80005-X }}</ref> In dogs it is used for the treatment of infections with ]s such as '']'' and with ] such as '']''.<ref name=ncats>{{cite web | url = https://drugs.ncats.io/substance/XVB7982801 | title = Butamisole | publisher = ] | work = Inxight Drugs }}</ref> It acts as a ] ] that causes sustained muscle contraction in the parasite followed by depolarizing neuromuscular blockade which leads to paralysis.<ref name=ncats/> author = B. T. Alford, G. T. Wang, T. R. Garces, R. B. Dougherty, R. E. Bradley }}</ref> It is an ] of the ] class.<ref>{{Cite journal | doi = 10.1016/S1090-0233(05)80005-X | title = Modes of action of anthelmintic drugs | date = 1997 | last1 = Martin | first1 = R.J. | journal = The Veterinary Journal | volume = 154 | issue = 1 | pages = 11–34 | pmid = 9265850 }}</ref> In dogs it is used for the treatment of infections with ]s such as '']'' and with ] such as '']''.<ref name=ncats>{{cite web | url = https://drugs.ncats.io/substance/XVB7982801 | title = Butamisole | publisher = ] | work = Inxight Drugs }}</ref> It acts as a ] ] that causes sustained muscle contraction in the parasite followed by depolarizing neuromuscular blockade which leads to paralysis.<ref name=ncats/>


==References== ==References==

Revision as of 13:49, 24 December 2024

Pharmaceutical compound
Butamisole
Identifiers
IUPAC name
  • 2-Methyl-N-thiazol-6-yl)phenyl]propanamide
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H19N3OS
Molar mass289.40 g·mol
3D model (JSmol)
SMILES
  • CC(C)C(=O)NC1=CC=CC(=C1)C2CN3CCSC3=N2

Butamisole is a pharmaceutical drug used in veterinary medicine. It is an anthelmintic of the imidazothiazole class. In dogs it is used for the treatment of infections with whipworms such as Trichuris vulpis and with hookworm such as Ancylostoma caninum. It acts as a nicotinic acetylcholine receptor agonist that causes sustained muscle contraction in the parasite followed by depolarizing neuromuscular blockade which leads to paralysis.

References

  1. B. T. Alford, G. T. Wang, T. R. Garces, R. B. Dougherty, R. E. Bradley (1979). "The efficacy and safety of injectable butamisole in dogs". Veterinary Medicine & Small Animal Clinician. 74 (4): 487–495.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. Martin, R.J. (1997). "Modes of action of anthelmintic drugs". The Veterinary Journal. 154 (1): 11–34. doi:10.1016/S1090-0233(05)80005-X. PMID 9265850.
  3. ^ "Butamisole". Inxight Drugs. National Center for Advancing Translational Sciences.
Categories:
Butamisole: Difference between revisions Add topic