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GPR19
Identifiers
Aliases	GPR19, G protein-coupled receptor 19
External IDs	OMIM: 602927; MGI: 892973; HomoloGene: 4476; GeneCards: GPR19; OMA:GPR19 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) Band 12p13.1 Start 12,660,890 bp End 12,696,207 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6|6 G1 Start 134,846,056 bp End 134,875,541 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad Brodmann area 23 endothelial cell middle temporal gyrus primary visual cortex ganglionic eminence cerebellar hemisphere Pituitary Gland right hemisphere of cerebellum Top expressed in spermatocyte medial ganglionic eminence spermatid Rostral migratory stream humerus seminiferous tubule zygote Pituitary Gland fibula suprachiasmatic nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function signal transducer activity G protein-coupled receptor activity Cellular component integral component of plasma membrane membrane integral component of membrane plasma membrane cilium Biological process signal transduction G protein-coupled receptor signaling pathway neuropeptide signaling pathway chemical synaptic transmission feeding behavior Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2842 14760 Ensembl ENSG00000183150 ENSMUSG00000032641 UniProt Q15760 Q61121 RefSeq (mRNA) NM_006143 NM_001167693 NM_001167694 NM_001167695 NM_001167696 NM_001167697 NM_001167699 NM_001167700 NM_008157 NM_001362048 NM_001362049 NM_001362050 NM_001362051 NM_001362052 RefSeq (protein) NP_006134 NP_001161166 NP_001161167 NP_001161168 NP_001161169 NP_001161171 NP_001161172 NP_032183 NP_001348977 NP_001348978 NP_001348979 NP_001348980 NP_001348981 Location (UCSC) Chr 12: 12.66 – 12.7 Mb Chr 6: 134.85 – 134.88 Mb PubMed search
Wikidata
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Probable G-protein coupled receptor 19 is a protein that in humans is encoded by the GPR19 gene. GPR19 has been proposed as the receptor for the peptide hormone adropin.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000183150 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000032641 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: GPR19 G protein-coupled receptor 19".
6. Stein LM, Yosten GL, Samson WK (March 2016). "Adropin acts in brain to inhibit water drinking: potential interaction with the orphan G protein-coupled receptor, GPR19". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 310 (6): R476 – R480. doi:10.1152/ajpregu.00511.2015. PMC 4867374. PMID 26739651.

Further reading

• O'Dowd BF, Nguyen T, Lynch KR, Kolakowski LF, Thompson M, Cheng R, et al. (October 1996). "A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain". FEBS Letters. 394 (3): 325–329. doi:10.1016/0014-5793(96)00901-5. PMID 8830667. S2CID 1484916.
• Montpetit A, Sinnett D (1999). "Physical mapping of the G-protein coupled receptor 19 (GPR19) in the chromosome 12p12.3 region frequently rearranged in cancer cells". Human Genetics. 105 (1–2): 162–164. doi:10.1007/s004390051080. PMID 10480372.
• Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Research. 12 (2): 117–126. doi:10.1093/dnares/12.2.117. PMID 16303743.

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